Richard W James Selected Research

Aryldialkylphosphatase (Paraoxonase)

9/2019	Low Serum Paraoxonase-1 Activity Associates with Incident Cardiovascular Disease Risk in Subjects with Concurrently High Levels of High-Density Lipoprotein Cholesterol and C-Reactive Protein.
1/2019	Serum paraoxonase 1 activity is paradoxically maintained in nonalcoholic fatty liver disease despite low HDL cholesterol.
12/2018	Serum paraoxonase-1 activity is associated with light to moderate alcohol consumption: the PREVEND cohort study.
1/2018	Serum paraoxonase-1 activity is inversely related to free thyroxine in euthyroid subjects: The PREVEND Cohort Study.
1/2017	The inverse association of HDL-cholesterol with future risk of hypertension is not modified by its antioxidant constituent, paraoxonase-1: The PREVEND prospective cohort study.
1/2017	Incident type 2 diabetes is associated with HDL, but not with its anti-oxidant constituent - paraoxonase-1: The prospective cohort PREVEND study.
2/2016	Serum paraoxonase-1 activity and risk of incident cardiovascular disease: The PREVEND study and meta-analysis of prospective population studies.
8/2014	Serum paraoxonase-1 activity is more closely related to HDL particle concentration and large HDL particles than to HDL cholesterol in Type 2 diabetic and non-diabetic subjects.
11/2011	Effects of paraoxonase activity and gene polymorphism on coronary vasomotion.
10/2006	Postprandial modulation of serum paraoxonase activity and concentration in diabetic and non-diabetic subjects.

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Richard W James Research Topics

Disease

10	Cardiovascular Diseases (Cardiovascular Disease) 09/2019 - 06/2003
10	Atherosclerosis 09/2019 - 02/2003
5	Reperfusion Injury 01/2019 - 04/2012
5	Type 2 Diabetes Mellitus (MODY) 01/2017 - 03/2008
5	Coronary Disease (Coronary Heart Disease) 11/2011 - 03/2002
4	Inflammation (Inflammations) 09/2019 - 06/2005
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2019 - 04/2005
4	Infarction (Infarctions) 01/2019 - 05/2013
4	Hypertension (High Blood Pressure) 01/2017 - 06/2006
4	Vascular Diseases (Vascular Disease) 01/2014 - 04/2002
3	Myocardial Infarction 01/2019 - 03/2012
2	Chronic Renal Insufficiency 07/2019 - 02/2018
2	Ischemia 05/2013 - 04/2012
2	Wounds and Injuries (Trauma) 04/2012 - 01/2006
2	Obesity 05/2008 - 03/2008
2	Coronary Artery Disease (Coronary Atherosclerosis) 06/2006 - 04/2005
2	Poisoning 01/2006 - 11/2004
2	Hypercholesterolemia 09/2005 - 08/2005
2	Atherosclerotic Plaque (Atheroma) 02/2004 - 02/2003
1	Non-alcoholic Fatty Liver Disease 01/2019
1	Hypoxia (Hypoxemia) 01/2019
1	Fatty Liver 01/2019
1	Abdominal Obesity 01/2019
1	Chronic Kidney Failure (Chronic Renal Failure) 02/2018
1	Heart Diseases (Heart Disease) 01/2018
1	Dyslipidemias (Dyslipidemia) 01/2016
1	Diabetes Mellitus 01/2016
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2016
1	Heart Failure 03/2011
1	Necrosis 03/2011
1	Herpes Zoster 11/2010
1	Neoplasms (Cancer) 01/2010
1	Insulin Resistance 05/2008

Drug/Important Bio-Agent (IBA)

17	Aryldialkylphosphatase (Paraoxonase)IBA 09/2019 - 03/2002
11	EnzymesIBA 09/2019 - 03/2002
11	HDL CholesterolIBA 09/2019 - 09/2002
10	HDL LipoproteinsIBA 01/2019 - 02/2004
6	AntioxidantsIBA 01/2017 - 03/2002
6	Lipoproteins (Lipoprotein)IBA 01/2016 - 02/2004
5	LDL Lipoproteins (beta Lipoproteins)IBA 09/2019 - 11/2004
5	Apolipoprotein A-I (Apolipoprotein A1)IBA 01/2018 - 04/2005
4	ApolipoproteinsIBA 01/2018 - 04/2005
4	CholesterolIBA 04/2012 - 02/2003
4	oxidized low density lipoproteinIBA 11/2011 - 11/2004
4	Glucose (Dextrose)FDA LinkGeneric 05/2008 - 03/2002
4	LDL CholesterolIBA 03/2008 - 04/2005
3	Proteins (Proteins, Gene)FDA Link 07/2019 - 05/2012
3	Triglycerides (Triacylglycerol)IBA 01/2019 - 04/2007
3	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 02/2018 - 01/2016
3	LipidsIBA 01/2018 - 06/2003
3	p38 Mitogen-Activated Protein KinasesIBA 01/2006 - 12/2003
2	CytokinesIBA 02/2018 - 03/2011
2	arylesteraseIBA 01/2017 - 01/2017
2	ConnexinsIBA 03/2016 - 05/2012
2	Connexin 43 (Connexin43)IBA 03/2016 - 02/2003
2	Apolipoproteins E (ApoE)IBA 09/2015 - 06/2005
2	CollagenIBA 02/2004 - 02/2003
1	C-Reactive ProteinIBA 09/2019
1	salicylhydroxamic acid (SHAM)IBA 01/2019
1	MicroRNAs (MicroRNA)IBA 01/2019
1	AlbuminsIBA 02/2018
1	DNA (Deoxyribonucleic Acid)IBA 01/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 01/2018
1	EsterasesIBA 01/2017
1	Troponin IIBA 03/2016
1	Alanine (L-Alanine)FDA Link 03/2016
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2016
1	Interleukin-33IBA 09/2015
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2015
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 05/2013
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2012
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 04/2012
1	AutoantibodiesIBA 03/2012
1	AldosteroneIBA 03/2012
1	A-factor (Streptomyces)IBA 11/2011
1	Adenosine (Adenocard)FDA LinkGeneric 11/2011
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 11/2011
1	Interleukin-6 (Interleukin 6)IBA 03/2011
1	Phosphotransferases (Kinase)IBA 11/2010
1	CD36 AntigensIBA 11/2010
1	CarbohydratesIBA 09/2010
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2010
1	Insulin (Novolin)FDA Link 05/2008
1	Phytoestrogens (Phytoestrogen)IBA 05/2008
1	Apolipoproteins B (ApoB)IBA 04/2007
1	Interleukin-8 (Interleukin 8)IBA 01/2006
1	OrganophosphatesIBA 01/2006
1	Protein Kinases (Protein Kinase)IBA 09/2005
1	InterleukinsIBA 06/2005
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 06/2005
1	Interleukin-1 (Interleukin 1)IBA 06/2005
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 06/2005
1	Chemokine ReceptorsIBA 02/2004
1	CC ChemokinesIBA 02/2004
1	Chemokine CCL5IBA 02/2004
1	ChemokinesIBA 02/2004
1	Met- RANTESIBA 02/2004
1	HDL2 LipoproteinsIBA 02/2004

Therapy/Procedure

1	Catheter Ablation 01/2018